【摘要】 目的探讨儿童慢性淋巴细胞性甲状腺炎的临床表现特点,及如何提高确诊率。方法回顾性分析了45例慢性淋巴细胞性甲状腺炎患儿临床资料。结果45例中男10例,女35例。中位年龄9岁4个月,中位病程11个月。全部病例均有甲状腺弥漫性肿大,43例患儿TGAb升高,38例患儿TMAb升高,细胞病理学检查结果44例诊断为慢性淋巴细胞性甲状腺炎,并明确分型,1例误诊为Grave’s病。临床诊断和FNAB诊断结合,确诊慢性淋巴细胞性甲状腺炎44例,确诊率98.2%。全部患儿予以对症处理,临床转归良好。结论儿童慢性淋巴细胞性甲状腺炎临床表现不典型,易误诊;FNAB结合甲状腺自身抗体检查可作为儿童慢性淋巴细胞性甲状腺炎较可靠诊断手段;儿童慢性淋巴细胞性甲状腺炎近期预后良好,预后可能与细胞学类型相关。更多还原

【Abstract】 Objective To investigate the characteristic of chronic lymphocytic thyroiditis  CLT with children in order to improve the final diagnosis rate. Methods There were 45 cases of CLT with children whose clinical data was analysed retrospectively. Results There were 10 cases of boy and 35 cases of girl and the middle age was 9 years and 4 months and the middle history was 11 months. All children had diffuse goiter. There were 43 cases whose TGAb increased and 38 cases whose TMAb increased. There were 44 cases who got final diagnosis and the typings were clarified by cytopathology and only 1 case who was misdiagnosed as. Grave’s disease. The final diagnosis rate was 98.2%. All children were given corresponding disposal and the clinical turn-over was fine. Conclusions The clinical manifestation of CLT maybe is atypical and easy to misdiagnose. Cytopathology companying with thyroid autoantibody examination is the most trustworthy diplomacy for children CLT. The children CLT has a good eusemia which maybe correlate with the type of cytology.更多还原