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少弱精子症与精浆附性腺标志物的相关性分析

Study of the relationship between oligoasthenospermia and accessory gentital glands markers

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【作者】 邓顺美文任乾黄建初刘美意唐立新姜彦嘉陈爱平

【Author】 DENG Shun-mei,WEN Ren-qian,HUANG Jian-chu,LIU Mei-yi,TAN Li-xin,JIANG Yan-jia,CHEN Ai-ping(Guangdong Family Planning Institute Guangzhou510600China)

【机构】 广东省计划生育科学技术研究所广东省计划生育科学技术研究所 广东广州510600广东广州510600广东广州510600

【摘要】 目的分析少弱精子症患者精液参数与精浆附性腺标志物的相关性,探讨附性腺功能对男性生育力的影响。方法采用精液常规、精子形态、精浆附性腺标志物分析方法,检测正常供精者和门诊就诊的少弱精子症患者的精液相关指标。结果少弱精子症组正常形态精子百分数、精子穿透功能、精浆中性α-糖苷酶显著低于正常对照组。相关分析结果显示,少弱精子症患者组,精液量与精子活动率呈负相关(r=-0.415,P<0.05),精子数与形态呈正相关(r=0.393,P<0.05)。结论少弱精子症患者同时存在不同程度的附睾功能障碍,精子功能下降,精子畸形率显著升高,睾丸生精功能越低下,精子畸形发生率越高。

【Abstract】 Objective To verify the effect of the accessory gential gland on the male fertility.Methods the relevant seminal parameters of32normal donors and35patients with olioasthenospermia were measured by analysis of seminal routine,sperm morphology and accessory gentital glands markers.Results the percentage of normal spermatozoa,the function of sperm penetration through cervical mucus and the enzyme activity of neu-tralα-1,4-glucosidase significantly declined as compared to the control.There was a significant negative rela-tionship between the semen volume and the sperm motility for the oligoasthenospermia(r=-0.415,P<0.05),and a significant positive relationship between the sperm count and the sperm morphology(r=0.393,P<0.05).Conclu-sions The abnormal function of epididymis exists in the oligoasthenospermia.Sperm function for the oligoas-thenospermia declines with an increase of the percentage of the abnormal sperm.The poorer the spermatogensies function of the testisis,the higher the percentage of the abnormal sperm appears.

  • 【文献出处】 海南医学 ,Hainan Medical Journal , 编辑部邮箱 ,2005年01期
  • 【分类号】R698.2
  • 【被引频次】2
  • 【下载频次】105
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