【摘要】 目的:探讨促肾上腺激素释放激素(CRH)在妊娠期间的浓度变化,及其在早产预测中的作用。方法:随机选取本院产科523例早中晚期孕妇和早产患者,应用放射免疫方法检测各孕妇血浆中CRH的变化并进行组间比较。结果:在孕早期,CRH处于低水平分泌状态;进入孕中期以后,CRH明显呈直线上升直至孕晚期呈指数增长。早产组较对照组CRH明显升高(P<0.05)。结论:随着妊娠的进展,CRH在孕妇外周血中的浓度逐渐增加;母体血浆CRH可作为预测早产的可靠指标。更多还原

【Abstract】 Objective:To explore the variation of CRH in the plasma of pregnant women and the role of CRH on the prediction of premature labor.Methods: 523 pregnant women were randomly selected to detect the concentration of CRH in the plasma using radioimmunity.Results: In early pregnancy,the concentration of CRH was in low level,while increased dramactically in midtrimester pregnancy and late pregnancy.The level of CRH in preterm labor was higher than the control group.Conclusions: over time during pregnancy,the level of CRH in the plasma of pregnant women increased obviously.And the increasing concentration of CRH can be a reliable predictor for preterm labor.更多还原