【摘要】 目的:分析呼吸机相关肺炎(ventilatorassociatedpneumonia ,VAP)的病原学及药物敏感的情况。方法:回顾分析5 6例VAP患者的临床资料、病原菌构成以及药敏感试验结果。结果:16 9例机械通气患者有5 6例发生呼吸机相关性肺炎,发生率为33.4 % ,死亡率为35 .7% ;共培养出致病的革兰氏阴性杆菌5 0株,革兰氏阳性菌14株,占VAP居首的细菌是铜绿假单胞菌。结论:VAP感染的细菌以革兰氏阴性杆菌为主,且细菌的耐药率普遍较高,在治疗中应注重病原菌的培养和药物敏感试验,合理使用抗菌素。更多还原

【Abstract】 Objective:To analyze the aetiological characteristics and bacterial susceptibility in paatients with ventilator associated pneumonia.Methods:To review the clinical characteristics, aetiological flora and bacterial susceptibility in 56 patients with VAP. Result:Among 169 patients who were treated by mechanical ventilation, totally 56 of them appeared VAP. The incidence of VAP was 33.4%, Fatality ratereaches 35.71%; 50Gram-negative bacteria(GNB)were isolated,14 Gram-positive bacteria were isolated,The dcminant bacterium was Psedomonas aeruginosa in patients with VAP. Conclustion:The main kind of bacteriun in patients VAP was GNB,and all bacteria showed high rissitance to common antibiotics. Identification of aetiological bacteria and bacterial susceptibility is essential to select suitable antibiotics in the treatment of VAP更多还原