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荧光动力学分析法测定5种酮清除超氧自由基和羟基自由基的活性

Fluorescent kinetic analysis measurement of antioxidant properties of five xanthones against on superoxide and hydroxyl radicals

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【作者】 赫春香王杨曹璨王世盛

【Author】 HE Chun-xiang ~1,WANG Yang~1,CAO Can~1,WANG Shi-sheng~2 (1.School of Chemistry and Chemical Engineering,Liaoning Normal University,Dalian 116029,China;2.Dalian Institute of Chemical Physics,Chinese Academy of Science,Dalian 116023,China)

【机构】 辽宁师范大学化学化工学院中国科学院大连化学物理研究所 辽宁大连116029辽宁大连116029辽宁大连116023

【摘要】 利用荧光动力学分析法研究了5种酮化合物对超氧自由基(O2.-)和羟基自由基(.OH)的清除作用.利用邻苯三酚自氧化产生O2.-;利用Fenton反应产生.OH,向这2个反应体系中分别加入5种口山酮化合物,O2.-和.OH的产生速率明显降低.说明5种酮化合物对和有较强的抑制作用.探讨了酮化合物的结构与其抗氧活性的关系.

【Abstract】 The scavenging effects of five xanthones on superoxide radicals(O2·) and hydroxyl radicals((·OH)) has been studied by fluorescent kinetic analysis.The O2-· were produced by autoxidation of pyrogallol and ·OH were produced by the reaction of fenton,five xanthones was added to the two system solutions,the produced rate of O2-· and ·OH was reduced.Results showed five xanthones have the scavenging effects on O2· and ·OH.The relations between structure of xanthones and its antioxidative activities has been explored.

  • 【文献出处】 高师理科学刊 ,Journal of Science of Teachers College and University , 编辑部邮箱 ,2005年04期
  • 【分类号】O657.3
  • 【被引频次】4
  • 【下载频次】403
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