【摘要】 目的探讨血液甲醇浓度(M)测定在口服甲醇中毒治疗中的意义。方法根据一次成功抢救的临床资料,观察42例口服甲醇中毒患者的M、血二氧化碳结合力(CO2CP)、阴离子间隙(AG)和眼部症状/体征,按是否需要行血液透析治疗分为应接受HD治疗组(GHD)、非HD治疗组(GNHD);用气相色谱顶空进样法(GC)测定M;并按不同M水平进行分析。结果(1)两组间logM、CO2CP和AG均有显著差异;(2)当M在0.5～7.8mmol/L时,两组间例数无显著性差异。结论M测定在口服甲醇中毒治疗中有重要意义,M≤7.8mmol/L时,可能已需要HD治疗。更多还原

【Abstract】 Objective To study the significance of blood methanol(M) detecting in oral methanol poisoning.Methods M was measured in 42 oral methanol poisoning patients by gas chromatography(GC), 42 oral methanolpoisoning were divided to GHD and NGHD according to whether need to hemodialysis(HD), Carbon dioxidecombination power(CO2CP),Anion gap(AG),M and eye sign/symptom were observed. Results (1)The logM, CO2CP,AG in GHD patients were significant higher than those in NGHD respectively. (2)The cases, its M lies in 0.5～7.8mmol/L,were not obvious difference between the two groups. Conclussion It is important to measureblood methanol for the treatment in oral methanol poisoning. It is entirely possible to need hemodialysisin patients for oral methanol poisoning in spite of M≤7.8mmol/L.更多还原