【摘要】 目的　了解戊型肝炎的临床特点。方法　回顾性总结分析14 9例戊型肝炎临床资料。结果　①14 9例戊型肝炎中,单纯性戊型肝炎41例,平均年龄47.3 2±16.10岁;乙型与戊型肝炎重叠感染95例,平均年龄40 .17±14 .15岁(P <0 .0 5 ) ;②乙、戊型肝炎重叠感染者较单纯戊型肝炎者,虽然ALT和TBIL无显著差异(P >0 .0 5 ) ,但ALB明显降低,且病程长、并发症多(P <0 .0 5和P <0 .0 1) ;③全部病例中好转118例;死亡8例,其中乙、戊型肝炎重叠感染6例;④2 1例检测了血清甲胎蛋白,2 0～40 0ng/ml 11例,>40 0ng/ml 3例。结论　戊型肝炎临床上以成年人多见。HBV感染者容易感染HEV ,且致临床病程延长,并发症多,预后差。良性肝病患者AFP也可明显升高。更多还原

【Abstract】 Objective To explore the clinical features of viral hepatitis E.Methods The clinical data of 149 cases with hepatitis E were analyzed retrospectively.Results In 149 patients,41 were the simple infection of HEV with mean age of 47.32±16.1 years;95 were the superinfection of HBV and HEV with mean age of 40.17±14.15years (P<0.05).Comparison of the data from the 95 patients with the superinfection and 41 with hepatitis E showed that no significant difference in the level of ALT(438.75±571.38U/L vs.665.22±700.98U/L) and TBil(239.19±246.34μmol/L vs.169.24±122.66μmol/L,P>0.05),however,the level of ALB in the superinfection was significantly lower leading to longer course and more complications(P<0.05 and P<0.01);118 cases improved and 8 died,out of which,6 were the superinfection of HBV and HEV;AFP was tested in 21 cases,and in 3 cases were higher than 400ng/ml,11 were among 20～400ng/ml.Conclusion Hepatitis E was ofen seen clinically in the adult man.The large majority of the chronic hepatitis B patients were susceptible to HEV,with longer clinical course,much more complications and worse prognosis.The level of AFP could be apparently higher in the non-cancer liver diseases.更多还原