【摘要】 目的探讨武汉地区乙肝病毒(hepatitisBvirus,HBV)感染与胃癌(gastriccarcinoma)发生的关系。方法对武汉地区313例胃癌和313非胃癌的消化道肿瘤患者进行病例对照研究,通过非条件Logistic回归单因素和多因素分析筛选主要危险因素。结果有乙型肝炎病史者发生胃癌估计危险性为7.606(95%CI为3.679～15.722)。结论对乙型肝炎患者HBsAg、HBcAg、HBcAb阳性者应高度重视,定期复查全面查体对胃癌的早期诊断具有重要价值。更多还原

【Abstract】 Objective To explore the relationship between Hepatitis B virus infection(HBV) and gastric carcinoma.~Methods A case-control study was conducted based on the diagnosed HCC patients in Wuhan city from January 1, 2000 to July 31, 2003. The data obtained from 313 cases and 313 controls were first analysed by means of single variable analysis and then by the multivariate Logistic regression analysis.~Results The result showed that the history of HBV infection was closely associated with gastric carcinoma (OR=7.606,95%CI 3.679-15.722). The hislory of hepatitis was the major risk factor of gastric carcinoma.~Conclusion Special attention should be paid to the HBV with positive HbsAg, HBcAg, HBcAb.It is important to have regular examination for the early diagnosis of gastric carcinoma.更多还原