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新生儿溶血葡萄球菌败血症临床表现及其耐药性分析
Drug resistance and clinical manifestation of hemolytic staphylococci in neonatal septicemia
【摘要】 目的:了解溶血葡萄球菌新生儿败血症的临床表现,探讨该菌的耐药性和治疗对策。方法:用纸片法(K-B法)测定细菌的药物敏感度。结果:临床表现无特异性。血培养获48株溶血葡萄球菌,其中17例为耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)。经青霉素类、头孢菌素类、万古霉素治疗后均治愈。结论:溶血葡萄球菌新生儿败血症缺乏特异的临床表现。β-内酰胺类抗生素可用于对此类感染的治疗,对甲氧西林耐药菌株的感染可采用万古霉素。
【Abstract】 Objetive:To investigate the drug resistance and clinical manifestation of hemolytic staphylococci in neonatal septicemia.Methods:Susceptibility was measurated with K-B disc diffusion.Results:There was no characteristic of clinical manifestation.Through hemoculture,we got 48 hemolytic staphylococci stains and 17 of them were ethicillin-resistant coagulase-negative(MRCNS).All patients were cured by penicillin G,cephalosporins and vancomycin.Conclusion:Neonatal septicemia caused by hemolytic staphylococci is lack of specific clinical manifestation.Most stains are susceptible to β-lactam drugs,while vancomycin is always usable for methicillin-resistant stains.
【Key words】 Neonat; Septicemia; Hemolytic staphylococci; β-lactam; Vancomycin;
- 【文献出处】 儿科药学杂志 ,Journal of Pediatric Pharmacy , 编辑部邮箱 ,2005年06期
- 【分类号】R722.1
- 【被引频次】2
- 【下载频次】109