【摘要】 目的:探讨布洛芬和扑热息痛在儿科临床的退热效果和安全性,为临床选择口服退热药物提供参考。方法: 108例感染性发热患儿随机分为布洛芬组和扑热息痛组,布洛芬组予布洛芬8mg/(kg·次)顿服;扑热息痛组予对乙酰氨基酚15mg/(kg·次)顿服。结果:布洛芬组60min体温下降幅度明显大于对乙酰氨基酚组(t= 2. 75,P< 0. 01),最大作用时间及退热持续时间均有显著性差异(t= 3. 23、5. 01,P均< 0. 01)。结论:布洛芬和对乙酰氨基酚退热效果确切,但布洛芬退热作用更强更快,体温下降更明显和维持时间更长,可作为儿科临床医师第一线的退热药。更多还原

【Abstract】 Objective: To study the effect and security of brufen and paracetamol on pediatric antifebrile, and suggest orallytaking antifebrile in clinic practice. Methods: 120 infected children were divided into two groups. The brufen group were given 8 mg/kg ibuprofen and the paracetamol group 15 mg/kg acetaminophen every time. Results: Compared with the paracetamol group, the brufen group defervesced much quicker in a period 60 minutes, and its effective time is longer too. Conclusions: Both of brufen and paracetamol are safe and effective pediatric antifebrile. Generally, brufen is superior to paracetamol. It can be the first antifebrile for clinical practice.更多还原