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基于原子力显微镜技术的单个生物大分子压弹性研究
Investigation of the compression elasticity of single biomacromolecules by atomic force microscopy
【摘要】 单个生物大分子力学性质已经成为一个新兴的研究领域,近几年来由于单分子技术的不断发展,这个领域取得了很多突破性的进展。本文介绍了基于原子力显微镜技术的几种单分子压弹性测量技术及这些技术的具体应用,同时也简要阐述了这些技术的局限性。另外对这个领域的发展也进行了初步地探讨。
【Abstract】 The study of the mechanical properties of single biomacromolecules has emerged as a new field in which great advances have been made recently due to the developments in single molecular experimental techniques.Here we introduced some measurement techniques based on the atomic force microscopy for compression elasticity of single molecules,and demonstrated the concrete applications and the limitations of these techniques.In addition,the advances in this exciting field were also prospected.
【关键词】 生物大分子;
压弹性;
原子力显微镜;
【Key words】 biomacromolecules; compression elasticity; atomic force microscopy;
【Key words】 biomacromolecules; compression elasticity; atomic force microscopy;
【基金】 国家自然科学基金资助项目(No.10335070,No.10304011).~~
- 【文献出处】 电子显微学报 ,Journal of Chinese Electron Microscopy Society , 编辑部邮箱 ,2005年03期
- 【分类号】Q71-3
- 【被引频次】12
- 【下载频次】282