【摘要】 鸡的体内器官表现出明显的左右不对称性,这些不对称性的确立发生在胚胎发育的早期,并且要求多种机制共同筹划和有序进行。对于从亨氏节(Hensen’s node)到机体原基的左右信息传递的基因网络已经有了较清楚的阐述。有助于我们对这种机制的理解。以鸡胚为模式动物进行不对称性发生和发育的研究具有多种优点,文章以鸡胚为发育模式,对器官不对称性发育的分子机理,研究方法和未来的研究趋势进行了较为详细的介绍和论述,以期丰富我们对器官不对称发育的理解。更多还原

【Abstract】 The establishment of chick internal organs asymmetries about the left-right axis occurs during early chick embryo development and requires the concerted and sequential action of several mechanisms.We have known genetic network about transmission of left-right information from Hensen’s node to the organ primordia.Many experiments in the chick embryo model have contributed crucially to our current understanding of such mechanisms.We also point out the chicken embryo model presents several advantages.Here we summarize the molecular mechanisms,study methods and study directions about development of chick internal organs asymmetries to boost up our knowledge of left-right organ asymmetry in the future.更多还原