【摘要】 将三种不同粒径的金纳米粒子组装到经 1,6 -己二硫醇修饰的金表面 ,借助于石英晶体微天平 (QuartzCrystalBalance,QCM)实时监测金纳米粒子的自组装动力学过程 ,结合Michaelis-Menten动力学模型 ,并比较了相应的自组装动力学参数 ,从而得出金纳米粒子粒径大小对金表面粒子组装动力学的影响。实验表明 ,粒径较小的粒子形成单分子层的速率比粒径较大的粒子快 ,而形成多分子层的速率比粒径较大的粒子慢。这一结果对合理选择粒子大小进而制成性能优良的生物传感器具有重要的意义。更多还原

【Abstract】 The kinetics of Au nanoparticles self-assembled on dithiol-modified Au substrate was investigated. During the formation of Au nanoparticles films on the Au substrate, QCM was used to monitor the progress of the surface reaction of Au nanoparticles with dithiol. Characteristics could be accurately modeled by the well known Michaelis—Menten model. Accordingly, The adsorption rate constants were calculated out for Au nanoparticles with three different sizes. It was found that the rate of formation of the first monolayer with relatively smaller particles is faster than larger particles, whereas for larger particles the multilayer formation rate is much faster than smaller particles.更多还原