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红花岩黄芪新天然产物研究

A new natural product from the roots of Hedysarum multijugum

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【作者】 王伟梁鸿王邠涂光忠陈虎彪赵玉英

【Author】 WANG Wei1, LIANG Hong1, WANG Bin1, TU Guang-zhong2,CHEN Hu-biao1,ZHAO Yu-ying 1△(1. Department of Natural Medicines, Peking University School of Pharmacentical Sciences, Beijing 100083,China; 2. Beijing Institute of Microchemistry)

【机构】 北京大学药学院天然药物学系北京微量化学研究所北京大学药学院天然药物学系 北京100083北京100083北京100083

【摘要】 目的:研究红花岩黄芪HedysarummultijugumMaxim.的化学成分。方法:采用溶剂法和各种色谱技术进行分离,根据化合物的理化性质以及多种谱学数据鉴定其结构。结果:从红花岩黄芪根中分离鉴定了7个化合物,分别为warangalone4′methylether(1),阿佛洛莫生(2),5,7二羟基4′甲氧基异黄酮7OβD葡萄糖苷(3),芒柄花素苷(4),柚皮素5,7二O葡萄糖苷(5),芹菜素(6)和水仙苷(7)。结论:化合物1是新天然产物,其余化合物为首次从该植物中分离得到。

【Abstract】 Objective: To study the chemical constituents of the roots of Hedysarum multijugum Maxim. Methods: Compounds were isolated and purified by solvent and column chromatographic methods, and their structures were determined on the basis of physico-chemical properties and spectroscopic data. Results: Seven compounds warangalone-4′-methyl ether(1), afrormosin (2), sissotrin (3) and ononin (4), naringenin-5, 7-di-O-β-D-glucopyranoside (5), apigenin (6) and narcissin (7) were obtained from the roots of Hedysarum multijugum. Conclusion: Compound 1 is a new natural product, and other compounds; are obtained from the plant for the first time.

【基金】 国家自然科学基金(20372002)资助~~
  • 【文献出处】 北京大学学报(医学版) ,Journal of Peking University(Health Sciences) , 编辑部邮箱 ,2005年05期
  • 【分类号】R282;
  • 【被引频次】14
  • 【下载频次】384
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