【摘要】 目的观察大剂量免疫球蛋白(IVIG)联合甲基强的松龙(甲强龙)治疗格林-巴利综合征(GBS)的效果。方法对20例GBS患儿使用大剂量IVIG联合甲强龙治疗72 h后进行疗效评价。结果治疗前后患儿在四肢肌肉麻痹,颅神经麻痹(包括Ⅶ、Ⅸ、Ⅹ对颅神经),呼吸肌麻痹方面无明显变化(P>0.05)。结论大剂量IVIG联合甲强龙早期治疗GBS可有效抑制麻痹进展,尤其是呼吸肌麻痹进展,减少人工呼吸机通气应用,降低死亡率。更多还原

【Abstract】 AimTo observe therapy effect of high-dose human gamma globulin in combination in medron for children with acute Guillian-Barr’e syndrome.MethodsThe paralysis results were evaluated in72h after high-dose human gamma globulin in combination in medron therapy for twenty children with acute Guillian-Barr’e syndrome in recent years.Results The paralysis in four limbs,cranial nerves(includingⅦ、Ⅸ、Ⅹpairs)and respiratory muscles did not change significantly befor,after therapy.ConclusionsThe early therapy of high-dose human gamma globulin in combination in medron for children with acute Guillian-Barr’e syndrome can bring effect to control paralysis progress,particularly in respiratory paralysis progress,reduce to use artificial respirator and lower death rate.更多还原