【摘要】 目的:研究急性心肌梗塞阴虚病机与血浆一氧化氮、内皮素水平的相关性。方法:根据中医阴虚辨证标准将98例急性心肌梗塞患者分为非阴虚组、阴虚组,后者又分为典型阴虚组与非典型阴虚组,均于发病后24～72h内清晨空腹抽取静脉血测血浆一氧化氮、内皮素水平,并与30例健康人作对照,比较各组间的差异。结果:急性心肌梗塞患者与正常组比较,血浆一氧化氮水平降低、内皮素水平升高(P<0.01)。阴虚组与非阴虚组比较,血浆内皮素水平升高(P<0.01),血浆一氧化氮水平差异无显著性。典型阴虚组与非典型阴虚组比较,血浆一氧化氮水平明显降低(P<0.01),血浆内皮素水平差异无显著性。结论:急性心肌梗塞患者阴虚病机与血浆内皮素及一氧化氮水平相关。更多还原

【Abstract】 Objective: To study correlativity of Yin-deficiency pathogenesis of acute myocardiac infarction with plasma nitric oxide(NO) and endothelin (ET) levels. Methods: According to differentiation criteria for TCM Yin-deficiency. 98 cases of acute myocardiac infarction were divided into non-Yin-deficiency group and Yin-deficiency group. The latter was divided again into typical Yin-deficincy group and atypica Yin-deficincy group. Within 24～72h after attack, venous blood of fasting in morning was taken and plasma NO and ET levels were determined, with 30 healthy persons used as controls. Results: Plasma NO level decreased and ET level increased in the patient of acute myocardiac infarction as compared with controls (P<0. 01). Plasma ET level increased in the Yin-deficiency group as compared with the atypical Yin-deficiency group (P<O. 01). Plasma NO level decreased in the typical Yin-deficiency group compared with the atypical Yin-deficiency group (P<O. 01). Conclusion: Yin-deficiency pathogenesis of acute myocardiac infarction is correlated with plasma ET and NO levels.更多还原