【摘要】 目的　分析肝外胆管癌患者的预后因素。方法　单因素按不同水平分层的人时死亡率计算方法和多因素Cox模型分析预后因素。结果 :手术方式和术后生存期的关系最为密切 ,行切除术的患者术后生存期明显延长 ,其次是病理类型、术后并发症和术后生存期关系亦非常密切 ,建立了肝外胆管癌术后生存危险状态函数。在此基础上比较了不同术式的 1、3、5年生存率。探查术的 1、3、5年生存率分别为 11.4 8%、0 .0 6 %、0 .0 0 3% ;外引流术的 1、3、5年生存率 30 %、16 .12 %、0 .31% ,切除术的 1、3、5年生存率分别为 6 9.2 3%、2 8.10 %、17.0 4 %。结论 :手术切除是治疗肝外胆管癌患者的最佳方案。更多还原

【Abstract】 Objective To analyze prognostic factors of patients with extrahepatic bile duct carcinoma. Methods Univariate analysis to calculate person-time mortality rate after stratifying by different levels and multivariate Cox model were used to analyze prognostic factors. Results The relation between operation type and postoperative survival period was the strongest and postoperative survival period was obviously lengthened for patients with resection. Pathological type and postoperative complication were also proved to be correlated with postoperative survival period and mathematic function was created to evaluate postoperative survival risk state of extrahepatic bile duct carcinoma. Based on this, survival rates of 1,3 and 5 year after different operation types were compared. The survival rates of 1,3 and 5 year after exploration were 11.48%、0.06%、0.003% respectively, the rates after extra-drainage were 30%、16.12%、0.31% and the rates were 69.23%、28.10%、17.04% for resection operation. Conclusion Operation resection was optimal scheme to cure patients with extrahepatic bile duct carcinoma.更多还原