【摘要】 目的　观察黄芪注射液联合川芎嗪注射液对老年椎动脉型颈椎病的疗效。方法　选择 80例住院病例 ,采用单盲法随机分为治疗组和对照组。治疗组给予黄芪注射液与川芎嗪氯化钠注射液联用 ,对照组给予维脑路通注射液静脉输注。两组均治疗两个疗程后评价疗效。结果　治疗后症状积分治疗组有明显下降(P <0 .0 1 ) ;旋颈试验阳性率治疗前 ( 80 .0 %)、治疗后 ( 1 2 .5 %)有明显改变 ;压顶试验阳性率治疗前 ( 77.5 %)、治疗后 ( 2 0 .0 %)比较亦有明显改变 ,治疗组血脂、血流变、血管活性物质 ;基底动脉SV、DV治疗后较治疗前均有明显改善 (P <0 .0 1 ) ;治疗组愈显率、有效率 ( 75 .0 %、92 .5 %)优于对照组 ( 5 2 .5 %、87.5 %)。结论　益气活血中药可增加颈总动脉、椎 -基底动脉血流量 ,降低血管阻力 ,改善脑血流量 ,纠正缺血的作用。更多还原

【Abstract】 Objective To observe the effect of Huangqi parenteral solution and ligustrazine on vertebral artery type of cervical spondylosis of old person Method:80 old hospitalized patients were randomly divided into treatment group and control group.The patients in treatment group were treated by Huangqi parenteral solution and ligustrazine, however the ones in control group were treated by troxerutin.After two courses the effect was evaluated.Results The symptom integral of treatment group were better than of control group(P<0.01).In treatment group, TG ,TC and LDL were all decreased than the control group(P<0.01).And also the hemorheology and basilar artery SV and DV were all ameliorated than the control one.Conclusion Huangqi parenteral solution and ligustrazine can decrease blood lipid,ameliorate blood kinetics; the drug can also antithrombosis and antiaggregate,decrease free radical and protect vessels and nerves, improve the blood vessel permeability and microcirculatory disorder; increase blood flow of common carotid artery and vertebra-basilar artery, reduce the vessel resisting force, ameliorate cerebral blood flow and redress ischemia.更多还原