【摘要】 目的研究中成药中重金属砷、铜的含量测定方法。方法以六味地黄丸(水蜜丸)为研究对象,采用微波消解样品,连续流动进样-氢化物发生原子吸收分光光度法测定砷含量,火焰原子吸收分光光度法测定铜含量。对消解温度、样品粉碎粒度、消解试剂用量、称样量、消解程序、消解时间等条件进行了考察。结果在优化后的消解条件下,砷的回收率在100.8～114.3%,铜的回收率在94.4%～110.2%。结论该方法简便、快速、灵敏、准确,可用于中成药中重金属的含量检测。更多还原

【Abstract】 Objective To establish a method for the determination of arsenic and copper in Chinese patent medicines.Methods Digested by microwave,the content of arsenic in Liuwei Dihuang Pill (prepared with water and honey) was measured by sequence flowing injection-hydride generation-atomic absorption spectrometry and content of copper by flame atomic absorption spectrometry. Effects of factors,including digestion temperature,smashing granularity of samples,proportion of digestive ingredients,volume of digestive agents,digestion procedure and digestion time,on the content determination were studied.Results Recoveries of arsenic and copper were 100.8%～114.3%and 94.4%～110.2%respectively under optimum conditions.Conclusion This method is simple and effective for the content determination of heavy mental in Chinese patent medicines.更多还原