【摘要】 目的 :观察后程加速超分割放疗加化疗治疗食管鳞癌的近期疗效。方法 :2 4例行后程加速超分割放疗的患者 ,分别于放射治疗的第 1、4周给予CF +DDP + 5 Fu化疗 ,5d为一个疗程 ,共 2个疗程。放疗结束时评定疗效。结果 :完全缓解率为 37.5 % ( 9/ 2 4 ) ,部分缓解率为 5 4 .2 % ( 13/ 2 4 ) ,总缓解率为 91.6 %。毒副反应的发生率较高。结论 :后程加速超分割放疗加化疗治疗食管鳞癌的近期疗效较好 ,虽毒副反应增加 ,但患者可以耐受更多还原

【Abstract】 Objective: To evaluate a recemt efficacy and toxicities of late course accelerated hyperfractionation radiotherapy (LAHR) combined withchemotheraphy for patients with esophageal squamous cancer.Methods: 24 patients with LAHR received two cycles of chemotherapy with leucoorin+5 fluorouracil+cisplatin for five consecutive days as one cycle in the first and fouth weeks. Efficacy was evaluated after radiotherapy.Result: Complete remission rate was 37.5% (9/24), partial remission rate was 54.2% (13/24), overall remission rate was 91.6% , incidence of toxic and side effects were higher.Conclusion: The combination late course accelerated hyperfractionation radiotherapy with chemotherapy for esophageal squamous cancer have a well recent effect, toxic and side effects are severer, but able to be tolerated.更多还原