【摘要】 目的:研究鹿角方的提取工艺。方法:用正交实验法等优选提取工艺中加水量、煎煮次数和时间及醇沉浓度。结果:优选得到的提取工艺参数为:鹿角加水12倍量单独煎煮3次,每次2h;淫羊藿等其余5味用水提醇沉法,先加水12倍量后2次加水10倍量,提取3次,每次1h,合并提取液,浓缩,加乙醇至70％沉淀后,回收乙醇。结论:优选的工艺能最大限度提取药效成分且重现性较好。更多还原

【Abstract】 Objective: To study the extraction procedure for Lujiaofang prescription. Methods: Orthogonal test was employed in selection of optimal conditions for the extraction procedure,including the optimal amount of water used in decoction, optimal times and duration of decoction and optimal alcoholic concentration in sedimentation. Results:The parameters were optimized as follows:Lujiao was decocted independently with 12 times of water, for 3 times, 2 hours per time. The other five components were processed by water extraction and alcohol sedimentation technique: water extracted 3 times, firstly with 12 times of water and the following 2 with 10 times respectively, 1 hour per time, the mixed decoction was concentrated and precipitated by adding alcohol to concentration of 70 % . Conclusion: The active ingredients are maximally extracted with good reproducibility.更多还原