【摘要】 目的:评价蛹虫草菌粉胶囊治疗慢性支气管炎的疗效和安全性。方法:本试验为Ⅱ期临床试验,采用多中心、随机、单盲、阳性药物平行对照法。425例患者分为试验组(n=315)和对照组(n=110),试验组给予蛹虫草菌粉胶囊,对照组给予金水宝胶囊,2药剂量均为1g,tid,疗程2个月。结果:试验组在咳嗽、咳痰、喘息、肺功能、胸部X线征象改善及综合疗效等方面均优干对照组(P<0.01)。试验组血常规、肝功、肾功、心电图等安全耐受性指标无明显变化(P>0.1)。结论:蛹虫草菌粉胶囊是治疗慢性支气管炎安全有效的药物。更多还原

【Abstract】 Objective: To evaluate the efficacy and safety of Cordyceps militaris capsules in treatment of chronic bronchitis. Methods:The multi-centers,randomized,single blind,and positive controlled study was conducted in 425 patients with chronic bronchitis. They were divided to receive Cordyceps militaris capsules in a dose of 1g tid for 2 months ( n = 315) or Jinshuibao capsule in a dose of 1g tid for 2 months ( n = 110). Results:The symptom of cough,sputum,and wheeze as well as lung function, chest X ray syndrome and comprehensive efficacy in the active group were significantly improved compared with control group (P< 0.01). No significant difference in blood routine examination, liver and renal functions, ECG and others between 2 groups were observed (P>0. 1). Conclusion : Cordyceps militaris capsules are effective in treatment of chronic bronchitis.更多还原