【摘要】 目的探讨危重病人氧利用率(O2UC)的变化与预后的关系。方法将71例危重病人分为两组:A组(死亡组23例),B组(存活组48例),另设C组(正常对照组)。所有患者于急诊入院时及入院后1,2,3,5,7和10 d分别抽取动、静脉血行血气分析并计算氧利用率,正常对照组仅作动、静脉血气1次并计算氧利用率。结果两组患者在24 h内氧利用率均显著高于正常对照组(P<0.01),且入院时A组氧利用率高于B组(P<0.05);入院第2天起,A,B两组氧利用率均迅速降低;其中A组氧利用率下降较B组更明显,且呈持续下降趋势;而B组于入院第5天起氧利用率逐渐回升到正常水平。结论危重患者氧利用率早期代偿性升高及后期降低的不同走势与病情程度、预后密切相关。氧利用率可作为危重病人动态的氧代谢监测指标。更多还原

【Abstract】 Objective: To explore the relationship between the change of oxygen utilization coefficient (O2UC) and prognosis in critically ill patients. Methods: 71 critically ill patients were divided into two groups: group A (23 Cases of the dead) and group B (48 Cases of the survival). The control group consisted of 30 normal individuals (group C). Gas analysis of arterial blood and central venous blood and calculation of O2UC were carried out in all 71 paitients on admission and 1, 2, 3, 5, 7, 10 day after admission respectively,and which was carried out only once in group C. Results: In 24 h, O2UC in group A and group B were significantly higher than that of group C (P<0.01), and O2UC in group A was higher than that of group B on admission. From the second day after admission, O2UC both in group A and group B decreased fast; O2UC in group A were obviously lower than that in group B and remained a lowerlevel; but from the fifth day after admission, O2UC in grorp B increased to normal Level gradually. Conclusion: The change of O2UC which increase compensatively early and decrease in late stage is related to patients, condition and prognosis. O2UC is a dynamic predictor of oxygen matabolism in the treatment of critically ill patients.更多还原