【摘要】 目的　探讨小鼠颈部心脏移植术的改进和研究心脏移植再灌注损伤及急性排异反应。方法　将Chen术式加以改进 ,将供心主动脉与受体颈总动脉行端侧吻合 ,进行 6 0次小鼠颈部心脏移植。结果　新方法使供心总缺血时间缩短至 30min ,7d存活率提高到 98%。结论　改进后的术式简单实用 ,提高了小鼠颈部心脏移植存活率 ,值得推广。更多还原

【Abstract】 Objective:To explore the improved technique of mouse cervical heterotopic heart transplantation and study cardiac transplantation rejective reaction and reperfusion injury.Methods:On the basis of Chen’s method , the donor heart aorta and the right common carotid artery of the recipient were anastomosed using the end-to-side suture technique.Results: The total ischemic time of the graft was shortened to 30 min, and the 7 day survival rate of the recipient was increased to 98% using the new technique.Conclusions: The developed method of cervical heart transplantation in mice was a new, simple and useful technique.更多还原