【摘要】 目的　探讨血清降钙素原 (PCT)在小儿肠炎中的诊断意义。方法　采用半定量固相免疫测定法测定 5 8例小儿肠炎患者血清PCT水平。结果　以血清PCT≥ 0 5ng/ml为细菌感染阳性阈值 ,则细菌性痢疾与轮状病毒性肠炎血清PCT水平相比较P >0 0 5 ,无显著性差异 ,特异性为 94 7%。中毒型细菌性痢疾与普通型细菌性痢疾比较P <0 0 0 5 ,有极显著性差异。普通型细菌性痢疾的敏感性为 2 0 0 % ,阳性预测值为 85 7% ,阴性预测值为 4 2 9% ;中毒型细菌性痢疾的敏感性 88 9% ,阳性预测值为 88 9% ,阴性预测值为 94 7%。结论　血清PCT在鉴别普通型细菌性痢疾与轮状病毒性肠炎时价值不大 ,但是PCT是细菌感染的重要指标 ,其诊断价值在于可反映急性细菌性痢疾的严重程度 ,PCT显著升高可作为中毒型细菌性痢疾的一个指标 ,具有一定的临床应用价值更多还原

【Abstract】 Objective To discuss the diagnosis value of the serum PCT in pediatric enteritis. Methods With the method of half-ration solid immunoassay, we mensurated the serum PCT level of 58 patients. Results Making positive threshold for bacterial infection by PCT≥0 5 ng/ml, combining with T-test, we obtain serum PCT. P >0 05 between the bacterial enteritis and rotavirus enteritis, which shows no significant difference. The specificity equal 94 7%, P <0 005 between the toxicosis enteritis and the common one, the significance is great. The sensitivity of common enteritis is 20 0%, positive predicitive value equal 85 7%, and the negative one is 42 9%. For the toxicosis enteritis, the corresponding index is 88 9%, 88 9% and 94 7%. Conclusion There is little value for serum PCT to distinguish common enteritis from Rotavirus enteritis. But PCT is critical index of bacterial infection, and the diagnosis value is to reflect the severity of acute bacterial enteritis. PCT’s obviously increasing can be used as an index for toxicosis enteritis, and it shows a certain appliance value for clinic.更多还原