节点文献

猪口蹄疫O型灭活疫苗PD50效检攻毒方式探索

Studies on the challenge manners for potency testing of FMD type O swine vaccine

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 郎洪武闫岩张荣军肖怀红杨汉春

【Author】 LANG Hong-wu~1, YAN yan~2, ZHANG Rong-jun~2, XIAO Huai-hong~2, YANG Han-chun~3(1. China Institute of Veterinary Drug Control, Beijing 100081; 2. Zhongmu Stock Lanzhou Biological Products Factory,Lanzhou, Gansu 730046; 3. China Agricultural University, Beijing 100094;China)

【机构】 中国兽医药品监察所中牧股份兰州生物药厂中国农业大学 北京 100081甘肃兰州 730046北京 100094

【摘要】 用10000TCID50的OR/80株F13细胞毒或用10000LD50的OR/80株乳鼠组织毒(ORMF8),通过肌肉注射途径、蹄踵球部或趾间皮内注射途径接种O型口蹄疫抗体阴性架子猪进行攻毒试验,三种途径均不能使试验猪产生规律性发病。

【Abstract】 Challenge testing were taken by three ways of intramuscular injection, intradermal injection into the heel bulbs of one foot or into the space of two toes with 10 000 TCID50 of OR/80F13 cell virus. The results showed that three ways could not make the pigs appear orderliness representative FMD infectious disease symptoms and pathological changes. Another challenge testing were taken by the same three ways with 10 000 LD50 of OR/80F8 (ORMF8) organnismic virus. The results showed that three ways also could not make the pigs appear orderliness representative FMD infectious disease symptoms and pathological changes.

  • 【文献出处】 中国兽药杂志 ,Chinese Journal of Veterinary Drug , 编辑部邮箱 ,2004年03期
  • 【分类号】S852.4
  • 【被引频次】2
  • 【下载频次】186
节点文献中: 

本文链接的文献网络图示:

本文的引文网络