【摘要】 目的　评价脑梗死急性期OCSP分型的真实性。方法　 1名神经科医生将连续就医、首次发生的急性脑梗死患者 14 3例按 0CSP分型法分型 ,然后与脑CT/MR结果盲法比较分型的准确性。结果　分型总正确率70 6 % (10 1/ 14 3) ,敏感度 :TACI 76 % (95 %CI:5 8%～ 94 % ) ,PACI 85 % (95 %CI:74 %～ 96 % ) ,LACI 6 0 % (95 %CI:4 8%～ 72 % ) ,POCI 73% (95 %CI:5 1%～ 95 % ) ;特异度 :TACI 98% (95 %CI:95 %～ 10 1% ) ,PACI 70 % (95 %CI:6 1%～79% ) ,LACI 93% (95 %CI:87%～ 99% ) ,POCI 96 % (95 %CI:92 6 %～ 99 4 % ) ;阳性预测值TACI 89% (95 %CI:75 %～10 3% ) ,PACI 5 2 % (95 %CI:4 0 %～ 6 4 % ) ,LACI89% (95 %CI:80 %～ 98% ) ,POCI73% (95 %CI :5 1%～ 95 % ) ;阴性预测值TACI 96 % (95 %CI:93%～ 99% ) ,PACI92 % (95 %CI:86 %～ 98% ) ,LACI72 % (95 %CI :6 3%～ 81% ) ,POCI96 % (95 %CI:92 6 %～ 99 4 % )。结论　脑梗死急性期OCSP分型的效度较好 ,神经体征变动和评价时间是影响分型准确性的主要因素。更多还原

【Abstract】 Objective To evaluate validity of OCSP classification in acute phase of cerebral infarction. Methods 143 consecutive patients with a first-ever cerebral infarction admitted to emergency room or hospital were respectively classified as four subtypes(TACI,PACI,LACI and POCI) by a neurologist according to criteria of OCSP classification. Accuracy of the classification were blindly compared to the findings of brain CT/MR. Results Total accurate rate of the classification was 70 6%(101/143). Sensitivity: TACI 76%(95% CI=58%～94%),PACI85%(95% CI=74%～96%),LACI 60%(95%CI=48%～72%),POCI 73%(95%CI=51%～95%);specificity: TACI 98%(95%CI=95%～101%),PACI 70%(95%CI=61%～79%), LACI 93%(95%CI=87%～99%),POCI 96%(95%CI=92 6%～99 4%); positive predictive value: TACI 89%(95%CI=75%～103%),PACI 52%(95%CI=40%～64%),LACI 89%(95%CI=80%～98%),POCI 73%(95%CI=51%～95%); negative predictive value:TACI 96%(95%CI=93%～99%),PACI 92%(95%CI=86%～98%), LACI 72%(95%CI=63%～81%),POCI 96%(95%CI=92 6%～99 4%). Conclusions The validity of OCSP classification in acute phase of cerebral infarction was better. Variation of neurological signs and evaluation time could influence the accuracy of the classification.更多还原