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桃红四物汤的实验研究(Ⅰ)——水与乙醇对桃红四物汤中芍药苷含量的影响

Experimental Studies on the Decoction Containing Four Drugs with Persicae and Carthami(Ⅰ) ——Effects of water and Ethanol on Paeoniflorin Content in the Decoction Containing Four Drugs with Persicae and Carthami

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【作者】 郭春燕张万明付煜荣王治宝张力王德宝白雪梅

【Author】 GUO Chun\|yan,ZHANG Wan\|ming,FU Yu\|rong,WANG Zhi\|bao,ZHANG Li,WANG De\|bao,BAI Xue\|mei (Zhangjiakou Medical College,Zhangjiakou 075000,China)

【机构】 张家口医学院张家口医学院 河北张家口075000河北张家口075000河北张家口075000

【摘要】 目的 :比较水提与醇提 (75 %乙醇 )对桃红四物汤中芍药苷的影响。方法 :采用高效液相色谱法测定桃红四物汤中单味药赤芍与复方中芍药苷的含量。结果 :复方所测成分含量显著高于单方 (P <0 0 1 ) ,复方醇提含量显著高于水提 (P <0 0 1 ) ,单方所测成分醇提与水提无显著性差异 (P >0 0 5 )。结论 :不同提取方法对复方成分溶出有显著影响

【Abstract】 Objective:To compare the content of Paeoniflorin in Decoction Containing Four Drugs with Persicae and Carthami by different solvents\|water and ethanol.Methods:We measured the content of Paeoniflorin in single drug \%Radix Paeoniae Rubra\% and group\|drug decoctions by HPLC.Results:The content of Paeoniflorin in group\|drug decoctions is higher than that in single drug \%Radix Paeoniae Rubra (P<0\^01)\%.In group\|drug decoctions,the content of Paeoniflorin with ethanol solvent is higher than that with water solvent( P< 0\^01).There was no significant difference in single drug \%Radix Paeoniae Rubra\% between water and ethanol solvent( P >0 05).Conclusion:Different solvent has significant effect on soluble substances extracted from group\|drug decoctions.

【基金】 河北省科技攻关计划指导项目 (0 1 2 761 1 54) ;张家口医学院青年基金资助项目 (Q2 0 0 1 0 3)
  • 【文献出处】 中国实验方剂学杂志 ,Chinese Journal of Experimental Traditional Medical Formulae , 编辑部邮箱 ,2004年04期
  • 【分类号】R289
  • 【被引频次】3
  • 【下载频次】231
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