【摘要】 目的　通过对 30 2名SARS临床确诊病人的血清抗体IgG检测结果进行分析 ,探讨流行病学接触史与血清抗体阳性率之间的相关性 ,以及接触史在临床诊断中的意义。方法　样品为北京市疾病预防控制中心在SARS流行期内采集的住院的和康复的SARS临床确诊病人的血清 ,按照流行病学接触史分组分析。采用ELISA抗体检测方法检测抗SARS病毒IgG。 结果　有流行病学接触史组的血清抗体阳性率与无接触史组具有显著差异。结论　流行病学接触史对SARS病例的诊断具有重要意义。在SARS临床诊断过程中应综合流行病学资料、实验室IgG检测结果和临床症状进行诊断。更多还原

【Abstract】 To investigate the relationship between the epidemiological contact history and the levels of IgG antibodies of patients with SARS in order to evaluate the significance of contact history in the clinical diagnosis of this illness,302 probable cases with clinically diagnosed SAES were subjected to study by retrospective analysis of the contact history and the results of IgG testing.The serum samples were collected from the hospitalized patients and the discharged patients during the epidemic period of SARS in Beijing area.The patients were grouped according to their contact histories,and the sera were tested for anti-SARS-Cov IgG by ELISA test kid.It was found that the difference of the positive rates of serum antibodies between cases with and without contact histories was statistically significant.It suggests that epidemiological contact history play an important role in the clinical diagnosis of SARS.Clinical symptoms,epidemiologic data the laboratory testing for IgG should be used together to make a real diagnosis of SARS.更多还原