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环孢素A滴眼液的研制
Research and preparation of cyclosporine A eyedrops
【摘要】 目的 :建立了环孢素A滴眼液的制备方法。方法 :采用蓖麻油制备环孢素A滴眼液 ,用HLPC测定制剂中环孢素A的含量 ,并对制剂的稳定性进行了考察。结果 :本研究研制的环孢素A滴眼液制备工艺简单 ,质量稳定 ,含量测定快速、准确。结论 :该制剂工艺可用于常规制备环孢素A滴眼液
【Abstract】 Objective:To establish the prescription and preparing procedure for the cyclosporine A eyedrops.Methods:The cyclosporine A eyedrops was prepared from castor oil.The cyclosporine A content of the preparation was determined by HPLC,and stability of the preparation was examined,too.Results:The results showed the procedure of preparation was simple,and the quantitative determination was quick,and accurate while the quality was reliable.Conclusion:The procedure described here can be uesed to prepare the cyclosporine A eyedrops.
【关键词】 环孢素A;
滴眼液;
含量测定;
稳定性;
【Key words】 Cyclosporine A; Eyedrops; Quantitative determination; Stability;
【Key words】 Cyclosporine A; Eyedrops; Quantitative determination; Stability;
- 【文献出处】 重庆医科大学学报 ,Journal of Chongqing Medical University , 编辑部邮箱 ,2004年05期
- 【分类号】R943
- 【被引频次】5
- 【下载频次】211