【摘要】 目的　探讨p185蛋白对乳腺癌的诊断意义.方法　采用免疫组化方法对乳腺癌、乳腺增生患者乳腺组织进行p185蛋白检测.结果　30例乳腺癌组织p185蛋白表达,其中12例阳性,阳性率为40%,26例乳腺增生组织未发现p185蛋白表达.结论　乳腺癌与乳腺增生组织p185蛋白的表达有显著差异(P<0.05),因此组织p185蛋白表达在鉴别乳腺癌和乳腺增生方面具有重要意义.更多还原

【Abstract】 ObjectiveTo investigate the diagnostic significance of tissue p185 expression for breast carcinoma.MethodsImmunohistochemistry technique was used to detect the expression of p185 protein in breast carcinoma and breast proliferation.ResultsThere are 12 positive expression of p185 protein in 30 breast carcinoma and the positive rate is 40%. There is no expression of p185 protein in 26 breast proliferation.ConclusionThere is significant difference comparing patients with breast carcinoma and patients with breast proliferation in p185 protein expression(P<0.05), therefore, the expression of tissue p185 has important value in distinguishing breast carcinoma from breast proliferation.更多还原