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淋巴细胞清除并血浆置换术治疗多发性骨髓瘤的疗效观察

Effetive Observation of the Lymphocyte Clearance and Plasmapheresis to the Multiple Myeloma

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【作者】 郑斌李爱华陈运贤

【Author】 ZHENG Bin 1,LI Ai hua 2,CHENG Yun xian 3 1.People’s Hospital of Sanshui District, Foshan 528100,China;2.Department of Sanshui Blood;3.1rd Hospital Affiliated of Sun yat sen University

【机构】 广东省佛山市三水区人民医院广东省佛山市三水区血站中山大学附属第一医院 528100

【摘要】 目的 了解淋巴细胞清除并血浆置换术降低多发性骨髓瘤 (MM )异常免疫球蛋白的作用与疗效。方法 用CS30 0 0 plus血细胞分离机对 2 8例MM患者行淋巴细胞清除并血浆置换术 ,观察淋巴细胞清除并血浆置换术后血沉 (ESR)、球蛋白 (GLB)的下降情况及临床症状的缓解效果。结果 每次淋巴细胞清除并血浆置换术后 ,患者ESR下降 4 1.5± 12 .6mm/h ,GLB下降 16 .9± 7.6g/L ,临床症状得以明显缓解。结论 淋巴细胞清除并血浆置换术能迅速有效地降低MM患者的GLB、ESR水平 ,并具有明显改善临床症状的优点

【Abstract】 Objective To comprehen the effects of declining the abnormal immunoglobulins and the therapeutic effects of the lymphocyte clearance and plasmapheresis to the multipl myeloma (MM).Methods It was made the lymphocyte clearance and plasmapheresis with CS3000 plus blood cells separator in 28 cases with MM;It was observed the decreased state of blood sedimentation rate (ESR),globulin (GLB),and the relief effects of the clinical symptoms after this process.Results The ESR the GLB declined 41.5 ± 12.6mm /hr and 16.9 ± 7.6g /L separately, and the clinical symptoms were obviously relief.Conclusion It has the advantages clinical symptoms significantly by the lymphocyte clearance and plasmapheresis in the cases suffered MM.

【基金】 广东省科委重点攻关项目基金资助
  • 【文献出处】 肿瘤防治研究 ,Cancer Research On Prevention and Treatment , 编辑部邮箱 ,2004年08期
  • 【分类号】R733.3
  • 【被引频次】4
  • 【下载频次】79
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