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胃癌MCD/MVD双标记检测及其意义

MCD/MVD were inspected with immunohistochemical double labeled and quantitative analysis in the gastric carcinoma and its significance

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【作者】 魏爱君张友元熊密黄望珍顾磊

【Author】 WEI Ai-jun, ZHANG You-yuan, XIONG Mi, et al Huangshi Central Hospital, Huangshi 435000, China

【机构】 湖北省黄石市中心医院华中科技大学同济医学院病理学教研室湖北省黄石市中心医院 435000435000

【摘要】 目的 探讨MCD、MVD与胃癌的关系。方法 免疫组化双标记检测 10 0例胃癌组织中MCD/MVD ,并作定量分析。结果 MCD/MVD≤ 0 .9时 ,癌累及浆膜病例较多 ;MCD/MVD >0 .9时 ,癌累及浆膜病例较少 ,两者比较 ,P <0 .0 5。结论 MCD/MVD的比值与癌浸润深度相关 ,是反映胃癌生物学行为的一个有用指标。

【Abstract】 Objective To probe into the relationship of mast cell density(MCD), microvessel density(MVD) and gastric carcinoma. Methods Immunohistochemical double labeled method was used for the observation of MCD/MVD in 100 cases of the gastric carcinoma and quantitative analysis. Results Patients of serosa with carcinoma of MCD/MVD ≤ 0.9 were more than of MCD/MVD> 0.9 , P < 0.05 . Conclusion A ratio of MCD/MVD was related to invasion depth of carcinoma, which was a useful index of reflecting on biological feature of the gastric carcinoma.

【关键词】 胃肿瘤肥大细胞微血管
【Key words】 Gastric tumorMast cellMicrovessel
【基金】 湖北省科技厅重点发展计划资助项目(2 0 0 0 2B2 1)
  • 【文献出处】 肿瘤防治研究 ,Cancer Research On Prevention and Treatment , 编辑部邮箱 ,2004年01期
  • 【分类号】R735.2
  • 【下载频次】36
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