【摘要】 目的评价血清白介素-6(IL-6)水平与心源性休克的关系。方法检测33例心源性休克患者的血清IL-6水平,并与健康对照组比较。结果血清IL-6水平心源性休克合并多脏器功能障碍综合征(MODS)患者为(389.46±56.21)pg?ml、单纯心源性休克组患者(93.65±19.21)pg?ml与健康对照组(5.46±2.79)pg?ml比较差别均有显著性意义(t=2.667、2.574,均P<0.01),合并MODS患者较单纯心源性休克患者明显增高(t=2.582,P<0.01)。血清IL-6水平>257.32pg?ml的患者易并发MODS。结论心源性休克患者血清IL-6水平升高,IL-6水平与心源性休克严重程度呈正相关(r=0.759,P<0.01),血清IL-6水平>257.32pg/ml的患者易并发MODS。更多还原

【Abstract】 Objective To evaluate the serum interleukin-6 (IL-6) levels in patients with cardiogenic shock. Methods Serum interleukin-6 levels were determined in 33 patients with cardiogenic shock and in 15 healthy subjects. Results Patients with cardiogenic shock had higher IL-6 levels than those in healthy subjects (93.65±19.21pg/ml vs 5.46±2.79pg/ml, P<0.01) . Patients complicated with multiple organ dysfunction syndrome (MODS) had even more higher IL-6 levels than cardiogenic shock (389.46±56.21 pg/ml vs 93.65±19.21 pg/ml, P<0.01). In this study cardiogenic shock patients with an IL-6 level >257.32pg/ml, all developed MODS. Conclusion Patients with cardiogenic shock is associated with high IL-6 levels; IL-6 level >257.32 pg/ml in patients with cardiogenic shock is a high-risk sign for development of MODS.更多还原