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肝癌切除术后门静脉与肝动脉区域化疗对机体的不同影响

The different effects of hepatic artery chemotherapy and portal vein chemotherapy on patients with liver cancer after surgery

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【作者】 陈德李悦蒋小峰林景泰胡以则

【Author】 CHEN De,LI Yue,JIANG Xiaofeng,et al.Department of Hepatobiliary Surgery,The Second Affiliated Hospital,Guangzhou Medical College,Guangdong,510260,China

【机构】 广州医学院第二附属医院肝胆外科广州医学院第二附属医院肝胆外科 510260中南大学在职博士生510260510260

【摘要】 目的 比较肝癌切除术后门静脉与肝动脉区域化疗对机体的不同影响。方法 对 4 2例原发性肝癌切除术后行肝动脉或门静脉化疗患者资料进行回顾性分析。结果 术后门静脉化疗组的骨髓抑制程度、肝功能损害、胃肠道不良反应均显著低于肝动脉化疗组 ,对细胞免疫的影响小于肝动脉化疗组。结论 经门静脉给药肝脏区域化疗是一种有效且副作用较小的肝癌综合治疗措施

【Abstract】 Objective To explore the different side effects of hepatic artery chemotherapy and portal vein chemotherapy on patients with liver cancer after surgery.Methods 42 cases were analyzed retrospectively,who underwent local hepatic artery chemotherapy or portal vein chemotherapy for primary hepatocellular carcinoma.Results The bone marrow depression and functional lesion of liver of portal vein chemotherapy were less than those of hepatic artery chemotherapy,and the portal vein chemotherapy had less immuno-suppresion than hepatic artery chemotherapy.Conclusion Portal vein chemotherapy has fewer side effects than that from hepatic artery on patients with primary hepatocellular carcinoma.

【基金】 1999年广东省医学科学技术研究基金项目(编号 :A19992 5 4)
  • 【文献出处】 中国基层医药 ,Chinese Journal of Primary Medicine Pharmacy , 编辑部邮箱 ,2004年08期
  • 【分类号】R735.7
  • 【被引频次】7
  • 【下载频次】35
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