【摘要】 目的　研究神经肽Y(NPY)与妊娠高血压综合征 (妊高征 )发病的关系。方法　检测 30例妊高征病人、30例正常妊娠妇女和 2 6例正常妇女的血浆NPY水平 ,以及妊高征病人分娩后 2周的血浆NPY水平。结果　妊高征组分娩前NPY水平明显高于正常妊娠组和正常对照组 ,差异均有显著意义 (均为P <0 0 1) ;正常妊娠组和正常对照组NPY水平比较 ,差异无显著意义 (P >0 0 5 ) ;妊高征组分娩后NPY水平明显下降 ,与分娩前比较 ,差异有显著意义 (P <0 0 1) ;而妊高征组分娩后NPY水平与正常妊娠组和正常对照组NPY水平比较 ,差异均无显著意义 (均为P >0 0 5 )。结论　妊高征病人的血浆NPY水平明显升高 ,NPY增加参与了妊高征的发病。更多还原

【Abstract】 Objective To investigate the changes and the clinical significance of plasma neuropeptide Y(NPY) concentration in patients with pregnancy induced hypertension(PIH).Methods Plasma NPY levels were detected in 30 patients with PIH,30 normal pregnant women and 26 normal women.Results The plasma NPY levels in patients with PIH were significantly higher than those of normal pregnancies and normal women(P<0.01).The plasma NPY levels were not significantly different in the normal pregnancies from those in normal women(P>0.05).After delivery,plasma NPY levels were significantly decreased in patients with PIH(P<0.01),which were the same as those of normal pregnancies and normal women(P>0.05).Conclusions The results suggest that the level of NPY in plasma is increased in women with PIH.Elevated plasma NPY levels may play a key role in the development of PIH.更多还原