【摘要】 目的　评价帕尼培南 倍他米隆治疗危重病人下呼吸道感染的临床疗效。方法　 14 0例下呼吸道感染的危重病人 ,随机分为治疗组 70例 ,对照组 70例。分别应用帕尼培南 倍他米隆和亚胺培南 西司他丁 ,剂量均为 2 0 g/d ,静脉滴注给药 ,疗程 7～ 14d。 结果　帕尼培南 倍他米隆和亚胺培南 西司他丁的临床有效率分别为 81 4%和 82 9% ,细菌清除率分别为 75%和 76 1%。均无明显不良反应。结论　帕尼培南 倍他米隆可作为重症下呼吸道感染有效和安全的抗生素更多还原

【Abstract】 Objective To evaluate the cli ni cal effect of panipenem betamipro on severe lower respiratory infection.Methods 140 critical ill patients suffered from severe lower respirat ory infection were divided randomly two groups:treatment group(n =70) and control group(n=70).The panipenem betamipron and imi penem cilastatin were respectively administrated in treatment group and control group,but the dosage(2.0g,qd)administration way(iv) and course(7～14 days)were the same.Results The clinical effective rate of panipenem beta mipron and imipenem cilastatin were respectively 81.4% and 82.9%, the bacterio clearance rate were respectively 75% and 76.1%.No obvious side reactions were found.Conclusion Panipenem betamipron can be used a safe and e ffective antibioltic to severe lower respiratory infection.更多还原