【摘要】 目的　观察聚四氢呋喃聚乳酸 (共聚物 C4 )作为可降解玻璃体替代物对孔源性视网膜脱离的治疗效果。　方法　 32只健康有色成年家兔 6 4只眼制成孔源性视网膜脱离模型 ,行玻璃体切割联合视网膜复位术 ,应用共聚物 C4 作为玻璃体替代物 ,观察视网膜复位情况及手术后并发症。　结果　手术后 3个月 ,视网膜复位率 96 .4 % ,白内障发生率 10 .9% ,青光眼发生率 5 .5 % ,共聚物乳化发生率 10 .2 %。　结论　共聚物 C4 可有效顶压视网膜裂孔 3个月 ,是一种有价值的玻璃体替代物。更多还原

【Abstract】 Objective To observe the therapeutic effect of poly tetrahydrofurfuryl-co-lactic acid (copolymer C 4) as the biodegradable vitreous substitutes on rhegmatogenous retinal detachment. Methods Vitreoretinal surgery with copolymer C 4 tamponades was performed on 32 pigmented rabbits (64 eyes) with rhegmatogenous retinal detachment. The rate of reattached retina and the post-operative complications were observed. Results Three months after the operation, reattached retina was found in 96.4%, glaucoma in 5.5%, cataract in 10.9%, and copolymer emulsion in 10.2% of all the eyes. Conclusion copolymer C 4 may withstand the retinal tear effectively for 3 months, and can be a valuable vitreous substitutes.更多还原