【摘要】 目的探讨介入、手术和生物联合治疗对中、晚期肾癌患者的效果。方法对52例中、晚期肾癌患者于手术治疗前行肾动脉造影后区域化疗、肾动脉主干栓塞、手术切除肿瘤、术后自体瘤苗注射的联合治疗(联合治疗组);对照组50例,采用单纯手术治疗。对两组肿瘤全切率、术中风险和术后生存率进行比较。结果联合治疗组手术肿瘤全切率为100%(52/52),手术切除的肿瘤组织平均体积2073cm3,较术前CT扫描的平均测量值2821cm3明显减小(t=1104,P=0000),术中平均输血280ml,平均手术时间100min,3年及5年生存率为73%(22/30)和50%(11/22);对照组肿瘤全切率为90%(45/50),术中平均输血量396ml,平均手术时间130min,3年及5年生存率为55%(17/31)和27%(7/26)。两组差异有显著性(P<005)。结论联合治疗可提高中、晚期肾癌的手术切除率,减少出血,降低手术风险并能提高术后生存率。更多还原

【Abstract】 Objective To observe the effect of the combined therapy of intervention,operation and biology in patients with middle advanced renal cell carcinoma. Methods Combined therapy was used in 52 cases as combined care groups and the single operational therapy was used in 50 cases as control group. Compare their resection rates, surgical risks and 3,5 years survival rates. Results In the combined care group, the excision rate was 100%, the average amount of blood transfusion during the operation was 280 ml, the average operation time was 100 minutes, and the 3,5 years survival rates were 73% and 50%; While in the control group, the results were 90%, 396 ml, 130 minutes, 55% and 27% respectively . There were significant differences between 2 groups( P <0 05). Conclusion Combined therapy could elevate resection rates and 3,5 years survival rates and decrease surgical risks.更多还原