【摘要】 目的　了解北京市围产期妇女生殖道感染 (reproductivetractinfection ,RTI)的发病情况及影响因素 ,为防治RTI提供依据。　方法　采用整群抽样的方法 ,对北京市 9个区的 2 4家医院产科门诊的孕妇共 36 6 6例进行生殖道感染检测 ,随机抽取其中的 6 4 1例RTI患者 (感染组 )与 6 0 2例正常孕妇 (对照组 )共 12 4 3例追访至分娩结束。　结果　在 36 6 6例围产期妇女中 ,RTI患病率2 4 .5 5 % ,滴虫性阴道炎患病率 1.85 % ,外阴念珠菌阴道病患病率 7.34% ,细菌性阴道病患病率13.6 1% ,宫颈沙眼衣原体感染患病率 1.34% ,妊娠合并梅毒患病率 2 .73‰ ,淋病患病率 0 .82‰ ,尖锐湿疣患病率 0 .5 5‰。感染组与对照组的死胎率分别为 1.4 0 %、0 .16 % (P <0 .0 5 ) ,胎膜早破率分别为 13.88%、5 .98% (P <0 .0 1) ,早产率分别为 1.2 5 %、0 .16 % (P <0 .0 5 ) ,羊水异常率分别为 6 .2 4 %、2 .82 % (P <0 .0 1) ,新生儿窒息率分别为 2 .34%、0 .83% (P <0 .0 5 )。围产期RTI的主要危险因素有家庭人均月收入≤ 10 0 0元、流动人口、平时性生活频繁、近 2周有不适感。　结论　围产期妇女生殖道感染情况及对母婴健康的影响不容忽视 ,应在北京市开展围产期RTI常规筛查及监测更多还原

【Abstract】 Objective To learn the prevalence and related factors of reproductive tract infections(RTI) in pregnant women and to find evidence for prevention. Methods By sampling method of clustering, 3666 pregnant women in 24 hospitals from 9 districts in Beijing were examined for RTI. Six hundreds and forty one RTI patients (RTI group) and 602 normal women (control group) were randomly chosen and followed up to the end of pregnancy. Results The prevalence of RTI was 24.55% (900/3666). The prevalence of trichomoniasis(68), vulva vaginal candidiasis(VVC)(269), bacterial vaginosis(BV)(499), chlamydia trachomatis(CT) of cervix(49), syphilis(10), neisseria gonorrhoeae(3) and condyloma accuminata(2) was 1.85%, 7.34%, 13.61%, 1.34%, 2.73‰, 0.82‰ and 0.55‰ respectively. The rate of fetal death (1.4%), premature rupture of membranes (13.88%), preterm labor (1.25%), abnormal amniotic fluid (6.24%) and neonatal asphyxia (2.34%) were significantly higher in the RTI group than that of the control (0.16%, 5.98%,0 16%, 2.82% and 0.83%, P < 0.05 or 0.01). The risk factors related to perinatal RTI were low family income less than RMB 1000 yuan per month per person, temporary resident, frequent sexual life, feeling uncomfortable within the last two weeks. Conclusions Attention should be paid to the prevalence of RTI in pregnant women and its adverse outcome. Routine screening and surveillance of RTI in pregnant women in Beijing were recommended.更多还原