【摘要】 以收率为考核指标,采用正交试验筛选出过氧化氢降解肝素制备相对分子量为1.2～2kD的肝素寡糖的最佳工艺条件。结果表明,优化条件为55℃、pH 7.0时一次性加入过氧化氢使其浓度达12%。更多还原

【Abstract】 The preparation of heparin oligosaccharides of Mr 1.2～2 kD by depolymerizing heparin with hydrogenperoxide were screened using orthogonal design with yield as evaluation parameter. The optimized reaction conditions wereas follows: added hydrogen peroxide at once up to concentration of 12% at 55℃ and pH 7.0.更多还原