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中国心房颤动现状的流行病学研究

An epidemiological survey of atrial fibrillation in China

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【作者】 周自强胡大一陈捷张仁汉李奎宝赵秀丽

【Author】 ZHOU Zi-qiang *,HU Da-yi,CHEN Jie,ZHANG Ren-han,LI Kui-bao,ZHAO Xiu-li. *Bejing Cardiology Department of People′s Hospital ,Peking University,Beijing 100044,China

【机构】 北京大学人民医院心脏中心北京大学人民医院流行病研究中心北京同仁医院心血管疾病诊疗中心 100044100044

【摘要】 目的 了解中国目前心房颤动 (房颤 )患病率、并发症以及服药情况 ,为进一步研究奠定基础。方法 选取 14个自然人群进行整群抽样调查 ,采用国际通用的标准化调查方法 ,在人群中进行以房颤为主要内容的心血管流行病学调查并统计结果。结果 中国房颤患病率总患病率 0 77% ,标准化率为 0 6 1%。年龄分组显示患病率有随年龄增加的趋势。男性病人房颤患病率高于女性(0 9%比 0 7% ,P =0 0 13)。所有房颤病人中瓣膜型、非瓣膜型及孤立性房颤所占比例分别为12 9% ,6 5 2 %和 2 1 9%。房颤病人中脑卒中以缺血性脑卒中为主 ,房颤病人脑卒中率明显高于非房颤人群 (12 1%比 2 3% ,P <0 0 1)。服药情况华法林为 1 7% ,阿司匹林为 37 9% ,洋地黄为37 9% ,β受体阻滞剂为 2 4 6 %。 结论 中国房颤患病率 ,年龄、性别、病因分组等均和国外相关资料趋势接近 ,脑卒中发病率高 ,但服药情况十分不理想 ,需要加强对房颤的控制。

【Abstract】 ObjectiveTo know the current prevalence of atrial fibrillation (AF) in China and contribute to further Chinese studies on AF in future. MethodsWe chose 14 natural populations from 14 different provinces across China. Using international standardized methods,we performed an epidemical study which was mainly on AF. ResultsThe crude rate of prevalence of AF in China is 0.77%,which would be 0.61% after being standardized. Also,it is increasing with aging. The prevalence is higher in men than in women (0.9% vs 0.7%,P =0.013). Among all the AF cases,valvular,nonvalvular,and lone AF were 12.9%,65.2%,and 21.9% respectively. Ischemic stroke was the most frequent type seen among AF cases and the stroke rate among cases with AF was significantly higher than that without (12.1% vs 2.1%,P <0.01). ConclusionsThe prevalence of AF in China,whether classified by age,gender or cause,is similar to the results from other countries,especially North America and Europe. The incidence of stroke among AF cases is rather high in China. However,patients with AF would not like to take the necessary medicine. Therefore it is advisable to enforce the control of AF. We will continue to do the follow-up in these populations.

【基金】 卫生部科技专项基金资助 (WKZ2 2 0 0 12 12 0 8)
  • 【文献出处】 中华内科杂志 ,Chinese Journal of Internal Medicine , 编辑部邮箱 ,2004年07期
  • 【分类号】R541.7
  • 【被引频次】2279
  • 【下载频次】4719
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