【摘要】 目的　探讨危重患者败血症早期快速诊断的可靠方法和降钙素原对危重患者败血症诊断的临床意义。方法　采用免疫发光法 (ILMA)对 12 0例中疑有败血症的危重患者测定血清降钙素原 (PCT) ,结合C反应蛋白 (CRP)测定和血培养结果进行分析。结果　PCT阳性 4 9例 ,CRP阳性 17例 ,血培养阳性 12例。感染灶组中PCT与CRP阳性率比较有明显差异 (P <0 .0 5 ) ;伴有多脏器功能障碍综合征与感染灶组比较 ,PCT阳性率有显著性差异 (P <0 .0 5 )。结论　PCT可以作为危重患者败血症早期诊断的指标 ,其动态变化亦可作为判断败血症预后的指标。更多还原

【Abstract】 Objective To explore the early and reliable diagnostic methods and clinical significance of procalcitonin (PCT) in critically ill patients with sepsis.Methods The levels of plasm PCT and C-reactive protein(CRP) were determined by immunoluminometric assay(ILMA) and blood culture was conducted in 120 critically ill patients with suspected sepsis.Results There were 49 cases with positive PCT,17 cases with positive CRP and 12 cases positive for blood culture among patients.In the group of having definitive infectious focus the PCT and CRP levels were significantly higher than the others(P<0.05).In the group of multiple organ dysfunction syndrome,PCT positive rate was higher than that of infectious focus group (P<0.05) .Conclusion PCT can be used as an early diagnostic marker of sepsis in critically ill patients,which dynamic changes can be a prognosis marker of sepsis.更多还原