【摘要】 目的　为了获得病理组织学诊断慢性胰腺炎 ,根据临床表现、影像学和外分泌功能检查临床疑为慢性胰腺炎的 4 7例患者 ,采用超声内镜引导下对胰腺行细针穿刺取得组织而进行病理学诊断。方法　 4 7例患者 ,男 2 8例、女 19例 ,年龄 4 7～ 6 9岁 ,平均 5 2 .3岁 ,病程在 3～ 2 1年之间 ,平均 6 .3年 ,临床疑为慢性胰腺炎、胰腺占位病变 ,并进行了相应的N 苯甲酰 L酪氨酰对氨苯甲酸 (BT PABA)试验、大便苏丹Ⅲ染色及胰腺CT检查的患者行超声内镜引导下细针穿刺 (EUS FNA) ,取得组织 ,进行病理学诊断。结果　 4 7例患者中 ,EUS FNA的病理组织学诊断慢性胰腺炎为 31例 (31/ 4 7、6 9% )。结论　通过EUS FNA进行病理学诊断 ,解决了以往慢性胰腺炎只有临床诊断没有病理诊断难题 ,从而为临床提供了诊断慢性胰腺炎的有效方法。更多还原

【Abstract】 Objective To evaluate the diagnostic value of endoscopic ultrasonography (EUS) guided fine needle aspiration (FNA) in patients with suspected chronic pancreatitis. Methods Forty seven patients including 28 males and 19 females (mean age 52.3 years, range 47～69 years) were enrolled into study. The diagnosis of chronic pancreatitis or pancreatic malignancy was based on results of BT PABA test, Sudan Ⅲ staining of stool and abdominal CT scanning, the mean course of disease was 6.3 year (range 3 21 year). Pancreatic tissue specimens were harvested by EUS guided FNA and investigated by histopathological study. Results Totally 31 cases (31/47, 69%) were diagnosed as chronic pancreatitis based on histopathological examination of the specimens taken by EUS FNA. Conclusion EUS FNA had the potential clinical value in diagnosis of chronic pancreatitis.更多还原