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高剂量率腔内放疗治疗宫颈癌临床分析

Clinical analysis of cervical cancer treated by radiotherapy with high-dose-rate intracavitary irradiation

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【作者】 陆寓非成慧君单娟王雯姚志伟谢翠峰

【Author】 LU Yu-fei, CHENG Hui-jun, SHAN Juan, et al(Department of radiotherapy, Henan Tumor Hospital, Zhengzhou 450008, China)

【机构】 河南省肿瘤医院放疗科河南省肿瘤医院放疗科 郑州 450008郑州 450008郑州 450008

【摘要】 目的 评价高剂量率腔内放疗治疗宫颈癌的疗效及并发症。方法 242例宫颈癌患者,其中Ⅰ期2例,Ⅱ期135例,Ⅲ期102例,Ⅳ期3例;鳞癌225例,腺癌16例,腺鳞癌1例,采用8MVX线或60Co γ线体外放疗及137Cs腔内放疗。结果 Ⅱ期、Ⅲ期患者5年生存率分别为75.60%和50.9%。放射性直肠炎及放射性膀胱炎发生率分别为11.2%和7.9%。结论 高剂量率腔内放疗是治疗宫颈癌的一种可行、有效的方法,疗效较好,并发症轻微,但对高危宫颈癌患者,需强调综合治疗。

【Abstract】 Objective To investigate the efficacy and side effects of the radiotherapy in treatment of cervical cancer. Methods 242 patients with cervical cancer were treated with 8MV-X rays or 60 Co-γ rays and 137 Cs intracavitary irradiation. Results The 5-years survival rate of stags- Ⅱ and 3333 patients was 75.6% and 50.9% respectively, and the incidences of postradiation cystitis and rectitis were 7.9% and 11.2% respectively. Conclusions Radiotherapy with high-dose-rate afterloading intracavitary irradiation is afeasible and effective therapy, but for local advanced cervical cancer,combination of chemotherapy and radiotherapy is necessary.

  • 【文献出处】 中国肿瘤临床与康复 ,Chinese Journal of Clinical Oncology and Rehabilitation , 编辑部邮箱 ,2004年05期
  • 【分类号】R737.33
  • 【下载频次】55
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