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电针“足三里”穴对酒精性脂肪肝大鼠模型的影响

Effects of electroacupuncture at “Zusanli” (ST 36) on alcoholic fatty liver rat model

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【作者】 王威于红朴顺福白丽

【Author】 WANG Wei1, YU Hong2, PIAO Shun-fu3, et al.(1.College of Acupuncture and Massage, Liaoning College of TCM, Shenyang 110032, China; 2.Shenyang City Hospital of Infectious Diseases; 3.Treatment Center of Diabetes, Liaoning Province)

【机构】 辽宁中医学院针灸推拿学院沈阳市传染病院辽宁省糖尿病治疗中心辽宁中医学院附属第一医院 沈阳110032

【摘要】 目的 :观察电针“足三里”穴对酒精性脂肪肝大鼠模型的防治效应 ,探讨其可能的作用机理。方法 :6 0 %乙醇灌胃建立酒精性肝损伤大鼠模型 ,观察电针“足三里”穴大鼠血清总胆固醇(Chol)、甘油三酯 (TG)及肝脏脂肪变性程度的变化。结果 :与自然恢复组比较 ,电针“足三里”穴可显著减轻肝细胞脂肪变 ,提高血清Chol,降低血清TG。结论 :电针“足三里”穴对酒精性肝损伤大鼠的作用机理可能为减轻肝细胞脂肪变 ,调整脂质代谢。

【Abstract】 Objective To observe preventing and treating effects of electroacupuncture at “Zusanli” (ST 36) on alcoholic fatty liver of the rat and study the mechanism. Methods The alcoholic liver injury rat model was established by intragastric infusion of 60% alcohol, and changes of serum total cholesterol (Chol), triglyceride (TG) and adipohepatic degrees of the liver were investigated after electroacupuncture at “Zusanli” (ST 36). Results Electroacupuncture at “Zusanli” (ST 36) could significantly reduce fatty degeneration of hepatic cells, and increase serum Chol level and decrease serum TG level as compared with the natural recovery group. Conclusion The mechanism of electroacupuncture at “Zusanli” (ST 36) for treatment of alcoholic hepatic injury is possibly relieving fatty degeneration of hepatic cells and regulating metabolism of lipids.

【基金】 辽宁省科技厅资助项目,编号 :2 0 0 2 3 2 0 2
  • 【文献出处】 中国针灸 ,Chinese Acupuncture & Moxibustion , 编辑部邮箱 ,2004年12期
  • 【分类号】R245.97
  • 【被引频次】30
  • 【下载频次】204
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