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三维适形放射治疗对局部中晚期胰腺癌的临床意义

Clinical significance of three-dimensional conformal technique for treating locally advanced pancreatic cancer

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【作者】 吴荣贾明轩郭启勇

【Author】 WU Rong, JIA Ming-xuan,GUO Qi-yong (Department of Radiation Oncology, The Second Affiliated Hospital, China Medical University, Shenyang 110004, China)

【机构】 中国医科大学附属第二医院放射肿瘤科中国医科大学附属第二医院放射肿瘤科 辽宁沈阳110004辽宁沈阳110004辽宁沈阳110004

【摘要】 目的 :用 6MV光子线的三维适形放射治疗计划与常规放疗计划进行比较 ,并治疗局部中晚期胰腺癌 ,观察近期疗效。方法 :10例确诊为局部中晚期胰腺癌患者 ,在三维治疗计划系统上 ,分别制定三维适形治疗计划和常规三野、四野治疗计划。比较靶区体积、等剂量线包括的组织体积及重要器官所受的照射剂量。结果 :对于吸收 4 0 %~ 5 0 %之间的照射剂量区 ,三维适形治疗所接受的照射体积明显小于常规三野、四野治疗 (P <0 0 1)。脊髓和左肾所受的平均放射剂量以三维适形治疗计划的剂量最低。结论 :对于中晚期胰腺癌 ,三维适形放射治疗较常放疗设计在剂量体积上有明显的改善 ,提供了使病人完成全程放疗的适宜方法。

【Abstract】 Objective: To campare the three-dimensional conformal radiotherapy of 6 mv photons and common techinques in treating locally advanced panreatic cancer and to observe the curative effects.Methods:In 10 patients with locally advanced pancreatic cancer, the treat plans of three-dimensional conformal were set up with the common three-field and four-field plan with the method using 6 MV photos. The average target volume,the average organs with different dosages, and the average dosage received in each key organs were compared. Results:For the treat dosage from 40% to 50%, the target volume was smaller by applying the three-dimensional conformal than that by common three-field and four-field treatment(P<0.01). The photon dosages were different between received by spinal cord and by left kidney. The photon dosage by three-dimensional conformal radiotherapy was the lonest.Conclusion:Three-dimensional conformal radiotherapy in treating pancreas cancer improve the dosage volume.It is an appropriate method to finish the total course of treatment of pancreatic cancer suffers.

  • 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,2004年02期
  • 【分类号】R735.9
  • 【被引频次】19
  • 【下载频次】72
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