【摘要】 目的 分析河南省传染性非典型肺炎的流行病学和临床学特征,为制定科学有效的预防控制措施提供依据。方法 采用个案调查方法,通过询问、检查及查阅病案的方式,收集临床诊断病例的人口学、流行病学和临床学的有关资料。结果 河南省疫情始于2003年4月16日,共发生临床诊断病例16例(1例由山西上报卫生部),其中13例为输入病例;发病时间集中在4月份;病例呈散发型。临床表现,发热是16个病人都具有的症状,最高体温达40℃,最低38℃。在16例病人中咳嗽有7人、乏力6人、胸闷5人、不适4人。其中5人有咳痰,3人痰带血丝。16例病人中白细胞低于正常值范围者3例,大于正常值者1例。16例病人X线胸片均表现为双肺多发片状、斑片状或棉絮状阴影,进展快。潜伏期1～13d,平均为5.8d。病程平均37.4d。16例病人痊愈出院后追踪观察6周均未见复发。结论 本次河南省发生的传染性非典型肺炎的疫情以输入病例为主,主要为外出务工人员,由于采取了积极的有效的预防控制措施使疫情未扩散,续发病例少,无流调和院内医务人员感染,效果良好。更多还原

【Abstract】 Objective To analyze tile epidemiological and clinical features of patients with Severe Acute Respiratory Syndrome (SARS), and to provide scientific basis for control measures. Methods The epidemiologic, clinical and diagnostic data from all the clinical cases were collected by case survey through inquiry face to face, physical examination and looking up medical records. Resuits The SARS prevalence began from 16 April, 2003 in Henan, there were 16 clinically diagnosed cases reported until May 6, 2003 (the time when the last case was reported in Henan, among which 1 case was reported to Health Ministry by Shanxi Province). 13 were imported cases. All the eases were occurred in April, 16 patients were scattered in 7 cities. The patients ranged from 20 to 53 years old, 7 were men and 8 were women. Their profession include worker (8 cases), farmer (6 cases), student (1 case) and doctor(1 case) .The first and most common symptom was fever (in 100%), which ranged from 38℃ to 40℃, followed by dry cough (7cases), asthenia (6 eases), chest distress (5 cases), discomfort (4 cases), expectoration (5 cases), blood tinged sputum (3 cases) .The initial blood count showed leukopenia (total white-cell count, <4×10~9 per liter) in 3 patients. 12 patients had normalwhite blood cell count (total white-cell count, 4×10~9～10×10~9 per liter) and lease hade increased (total white-cell count,>10×10~9 per liter).The white cell count continued to drop within the first few days after admission in 7 patients. Chest radiographys of the 16 patients showed air-space shadowing with multiple, bilateral areas of involvement.The incubation period in our patients was between 1 and 13 days, the average was 5.8 days. The average course was 37.4 days. All the 16 patients didn’t relapse after recovery tracking survey for 6 weeks. Conclusion The prevalence of SARS in Henan was caused predominantly by imported eases.The secondary tranmission only occurred in hospital and families because of close contact. There were only 3 secondary cases, no local health worker infected in this prevalence, which indicates that the control measures are effective.更多还原