【摘要】 目的　探讨门静脉区域化疗对原发性肝癌完全切除术后的复发和转移的预防效果。方法　 1997年10月至 2 0 0 0年 10月间 ,广州医学院附属第二医院对 4 2例原发肝癌手术切除后分别行肝动脉 (18例 )或门静脉(2 4例 )区域预防性化疗。结果　两组间的术后 1、3、5年总生存率差异无显著意义 (P >0 0 5 ) ,门静脉化疗组的1、3年无瘤生存率显著高于肝动脉化疗组 (P <0 0 5 )。结论　术后门静脉区域预防性化疗可预防和延缓肝癌切除术后的复发和转移。更多还原

【Abstract】 Objective To explore the effect of the portal vein local chemotherapy on tumor recurrence after surgical resection of primary hepatic carcinoma.Methods From Oct 1997 to Oct 2000,in Second Affiliated Hospital of Guangzhou Medical College 42 patients with primary hepatocellular carcinoma were performed chemotherapy through hepatic artery(18 cases) or portal vein (24 cases) after surgical tumor resection.Result The total survival rates at 1,3,5 years were no significant difference between the two groups(P>0.05). No-neoplasm survivals rates at 1,3 years in patients of portal vein chemotherapy group were longer than those in patients of the hepatic artery chemotherapy group (P<0.05). Conclusion Local chemotherapy through portal vein was an effective treatment in preventing tumor recurrence and metastasis after surgical resection of primary hepatocellular carcinoma.更多还原