【摘要】 人类基因组计划深刻地影响了药物研究和开发的思路和策略 ,生命科学的研究方法和技术与药物研究的结合日益紧密 ,计算机信息技术也越来越多应用到药物研究过程中来。本文以实例说明了虚拟筛选、配体垂钓以及靶标的发现与确证方法在药物研究中的应用更多还原

【Abstract】 The progresses from Human Genome Project have dramatically changed the strategy and methods of drug discovery and development.Meanwhile,new methods and techniques from life sciences and computer informatics have been also introduced into drug discovery.Here we demonstrate the applications of virtual screening,ligand fishing and drug target validation to drug study.更多还原